Underdeveloped extraocular muscles in the naked mole rat (Heterocephalus glaber)

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Central visual system of the naked mole-rat (Heterocephalus glaber).

Naked mole-rats are fossorial rodents native to eastern Africa that spend their lives in extensive subterranean burrows where visual cues are poor. Not surprisingly, they have a degenerated eye and optic nerve, suggesting they have poor visual abilities. However, little is known about their central visual system. To investigate the organization of their central visual system, we injected a neur...

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Digital dissection of the masticatory muscles of the naked mole-rat, Heterocephalus glaber (Mammalia, Rodentia)

The naked mole-rat, Heterocephalus glaber, of the family Bathyergidae is a subterranean rodent that feeds on underground roots and tubers and digs extensive tunnel systems with its incisors. It is a highly unusual mammal with regard to its social structure, longevity, pain insensitivity and cancer resistance, all of which have made it the subject of a great deal of research in recent years. Yet...

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Thermogenic changes with chronic cold exposure in the naked mole-rat (Heterocephalus glaber).

The naked mole-rat (Heterocephalus glaber) lives communally in a thermally buffered underground habitat. Here, it relies primarily on ectothermic (behavioral) mechanisms to maintain body temperature (T(b)). Outside this milieu, it is unable to effectively regulate T(b) and T(b) tracks that of ambient temperature (T(a)). Although naked mole-rats, in their natural habitat have little need for col...

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Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)

In all mammals, tissue inflammation leads to pain and behavioral sensitization to thermal and mechanical stimuli called hyperalgesia. We studied pain mechanisms in the African naked mole-rat, an unusual rodent species that lacks pain-related neuropeptides (e.g., substance P) in cutaneous sensory fibers. Naked mole-rats show a unique and remarkable lack of pain-related behaviors to two potent al...

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Cutaneous and periodontal inputs to the cerebellum of the naked mole-rat (Heterocephalus glaber)

The naked mole-rat (Heterocephalus glaber) is a small fossorial rodent with specialized dentition that is reflected by the large cortical area dedicated to representation of the prominent incisors. Due to naked mole-rats' behavioral reliance on the incisors for digging and for manipulating objects, as well as their ability to move the lower incisors independently, we hypothesized that expanded ...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2006

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.20.5.a826-b